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Ongoing Projects​

  • Physiological and pharmacological significance of formate-nitrite transporters in Toxoplasma gondii: ICMR Research Grant.​

  • Lipid and cyclic nucleotide signaling in Toxoplasma gondii: Wellcome Trust – DBT (India Alliance) Senior Fellowship.

  • Optogenetic Illumination of Toxoplasma Lytic Cycle: Indo-Japan Scholar Mobility Program (@Osaka University, Japan).

  • Computational Identification of Therapeutic Targets and AI-based Drug Repurposing in Parasitic Protists: Cross Disciplinary Research Fund by BITS, Pilani (co-PI: Poonam Goyal and Aneesh Chivukula).

  • Sustained Illumination of Natural Environment: BioCyTiH Foundation, India.

  • Optogenetic regulation of parasite signaling: Indo-German Science & Technology Cooperation (IGSTC) Women in Science, Engineering and Research (WISER) Program with Dr. Özlem Günay-Esiyok (Humboldt University of Berlin, Germany).

  • Proteomics-based identification of host determinants and diagnostic biomarkers of Toxoplasma infection: IGSTC–WISER Program with Dr. Ute Distler (University of Mainz, Germany).

  • ​Functional characterization of P4-ATPase and SERCA Proteins from the Obligate Intracellular Pathogen Toxoplasma gondii: DAAD DST Project-based Personnel Exchange Programme (PPP) with Dr. Bo Hojen Justesen, Ruhr University Bochum, Germany.

  • Host miRNAs as Molecular Determinants of Ocular Toxoplasmosis: Anusandhan National Research Foundation (ANRF) with Dr. Meetali Singh (Indian Institute of Science, Bangalore). 

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Previous Grants

  • Biosensor monitoring in Toxoplasma gondii: Indo-Japan Scholar Mobility Program (co-PI, Takeharu Nagai @Osaka University, Japan).​​

  • Pyruvate homeostasis in Toxoplasma gondii: DST-SERB Core Research Grant.​

  • A novel lipid-regulated calcium homeostasis in Toxoplasma gondii, German Research Foundation.

  • Functional and physiological significance of phosphatidylethanolamine biogenesis in Toxoplasma gondii, German Research Foundation.

  • Cyclic nucleotides-mediated ion homeostasis in the malaria parasite: German Research Foundation; co-PI: Alexander Maier (ANU).

  • Metabolic basis of obligate intracellular parasitism: German Research Foundation.

  • Optogenetic dissection of cyclic NMP signaling T. gondii: German Research Foundation, co-PI: Peter Hegemann.

  • Cyclic NMP signaling and metabolic regulation in T. gondii: German Research Foundation.

  • Synthesis vs. import of host-derived phospholipids by T. gondii: German Research Foundation; co-PI: Maik Lehmann.

  • Carbon metabolisms of acute and chronic stages of T. gondii: German Research Foundation.

  • Phosphatidylcholine synthesis as a drug target in T. gondii: Young scientist grant from European Society of Infectious Diseases and Microbiology.

  • Biogenesis of inositol-lipids in T. gondii: German Research Foundation, co-PI: Andreas Herrmann (HU, Berlin).

  • Modeling of lipid biogenesis in Toxoplasma-infected human cell: German Research Foundation, co-PIs: Herrmann Holzhütter (Charité, Berlin) and Richard Lucius (HU, Berlin).

  • High-throughput anti-coccidian drug screening using YFP-parasite, Novartis Animal Healthcare, co-PI: Richard Lucius (HU, Berlin).

  • In vivo parasite-host interactions in the Eimeria-mouse model. Manuela Schmid (doctoral student) & Nishith Gupta (host PI), Helmholtz Foundation.

  • Central carbon metabolism of T. gondii. Martin Blume (doctoral student) & Nishith Gupta (host PI), Helmholtz Foundation.

Funding Acknowledgements

DST
Wellcome Trust, DBT India
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India-Japan-Cooperative-Science-Programme
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Wellcome Trust
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International Collaborations

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HAU Wuhan
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SCAU
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